Square X-Pill

From Uncle George's Letter:"« Take a square 'S' pill before, as they 'save' your current configuration and allow to 'restore' it later. If you forget, effects are permanent. Hopefully, any X-PILL lab should be able to reverse most of them.»"

Primary Effects
Square X-pills are for getting your ideal portrait and trait combination. The first pill you take is like a save point that remembers your current portrait and gender. When you take your second or third pill, you will return to the saved portrait but leaves your gender the same, or return you to the saved gender if you are currently the saved portrait. Notably, this is one of the only ways to become single sexed after becoming intersexed.

Another thing to keep in mind, Square pills do not count towards the maximum pills you can take (i.e. they don't progress your headache).